Download E-books Happy Accidents: Serendipity in Major Medical Breakthroughs in the Twentieth Century PDF

By Morton A. Meyers

A fascinating and hugely available examine the brilliant function serendipity has performed in one of the most vital clinical discoveries within the 20th century.

Happy Accidents is an engaging, wonderful, and hugely obtainable examine the brilliant position serendipity has performed in the most vital clinical discoveries within the 20th century. What do penicillin, chemotherapy medicinal drugs, X-rays, Valium, the Pap smear, and Viagra have in universal? They have been each one came across unintentionally, stumbled upon within the look for whatever else. within the Nineteen Nineties, Pfizer had excessive hopes for a brand new drug that may enhance blood move to the guts. As they carried out trials on angina victims, researchers famous a startling influence: whereas the drug didn't have an effect on blood stream to the guts, it did impact blood circulation in other places! Now over six million American males have taken Viagra of their lifetime.

Winston Churchill as soon as acknowledged, “Men sometimes stumble around the fact, yet so much of them choose themselves up and hurry off as though not anything has happened.” in the medical neighborhood, a definite stigma is connected to likelihood discovery since it is badly visible as natural success. chuffed injuries definitely occur each day, however it takes intelligence, perception, and creativity to acknowledge a “Eureka, i discovered what I wasn't taking a look for!” second and be aware of what to do subsequent. In discussing scientific breakthroughs, Dr. Morton Meyers makes a cogent, hugely enticing argument for a extra inventive, instead of in basic terms linear, method of technological know-how. And it may well simply store our lives!
10 black-and-white photos

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Download E-books Suffering For Science: Reason and Sacrifice in Modern America PDF

From ugly self-experimentation to arduous theoretical calculations, tales abound of scientists willfully surrendering health and wellbeing, overall healthiness, and private pursuits for the sake in their paintings. What debts for the superiority of this coupling of information and pain-and for the odd assumption that technological know-how calls for such pain? during this lucid and soaking up heritage, Rebecca M. Herzig explores the increase of an ethic of "self-sacrifice" in American technology. Delving into many of the extra bewildering practices of the Gilded Age and the revolutionary period, she describes whilst and the way science-the meant common of all issues really apt and disinterested-came to depend upon an enthralled investigator prepared to include toil, risk, or even deadly dismemberment. With consciousness to transferring racial, sexual, and transnational politics, Herzig examines the agony scientist as a fashion to appreciate the fast transformation of yank lifestyles among the Civil struggle and international battle I.

Suffering for technological know-how finds greater than the fervour obtrusive in lots of clinical vocations; it additionally illuminates a nation's altering understandings of the needs of ache, the limits of cause, and the character of freedom within the aftermath of slavery.

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Download E-books Tinderbox: How the West Sparked the AIDS Epidemic and How the World Can Finally Overcome It PDF

By Craig Timberg

"Remarkable... reads like a detective novel."—The New Yorker

In this groundbreaking paintings that reads like a detective novel, longtime Washington Post reporter Craig Timberg and award-winning AIDS researcher Daniel Halperin inform the magnificent tale of the way Western colonial powers unwittingly sparked the AIDS epidemic after which fanned the flames. Drawing on impressive new technology, Tinderbox overturns the normal knowledge at the origins of this lethal pandemic, and in a riveting narrative that stretches from colonial Leopoldville to Eighties San Francisco to South Africa this present day, it finds how human palms unleashed this epidemic and will now triumph over it, if simply we examine the teachings of the prior.

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Download E-books To Explain the World: The Discovery of Modern Science PDF

A masterful statement at the background of technology from the Greeks to trendy instances, via Nobel Prize-winning physicist Steven Weinberg—a thought-provoking and critical e-book through essentially the most uncommon scientists and intellectuals of our time.

In this wealthy, irreverent, and compelling historical past, Nobel Prize-winning physicist Steven Weinberg takes us throughout centuries from old Miletus to medieval Baghdad and Oxford, from Plato’s Academy and the Museum of Alexandria to the cathedral institution of Chartres and the Royal Society of London. He exhibits that the scientists of historical and medieval instances not just didn't comprehend what we comprehend in regards to the world—they didn't comprehend what there's to appreciate, or the right way to know it. but over the centuries, throughout the fight to unravel such mysteries because the curious backward circulation of the planets and the increase and fall of the tides, the trendy self-discipline of technological know-how ultimately emerged. alongside the way in which, Weinberg examines ancient clashes and collaborations among technological know-how and the competing spheres of faith, expertise, poetry, arithmetic, and philosophy.

An illuminating exploration of how we give some thought to and research the realm round us, To clarify the World is a sweeping, formidable account of ways tricky it used to be to find the pursuits and techniques of contemporary technological know-how, and the effect of this discovery on human wisdom and development.

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Download E-books The Large Hadron Collider: The Extraordinary Story of the Higgs Boson and Other Stuff That Will Blow Your Mind PDF

By Don Lincoln

Since 2008 scientists have carried out experiments in a hyperenergized, 17-mile supercollider underneath the border of France and Switzerland. the big Hadron Collider (or what scientists name "the LHC") is without doubt one of the wonders of the fashionable world―a hugely subtle medical device designed to recreate in miniature the stipulations of the universe as they existed within the microseconds following the massive bang. between many amazing LHC discoveries, one resulted in the 2013 Nobel Prize in Physics for revealing facts of the life of the Higgs boson, the so-called God particle.

Picking up the place he left off in The Quantum Frontier, physicist Don Lincoln stocks an insider’s account of the LHC’s operational heritage and offers readers every little thing they should turn into good expert in this wonder of expertise.

Writing in regards to the LHC’s early days, Lincoln deals prepared perception into an coincidence that derailed the operation 9 days after the collider’s 2008 debut. A defective solder joint all started a sequence response that prompted an enormous explosion, broken 50 superconducting magnets, and vaporized huge sections of the conductor. The crippled LHC lay dormant for over a yr, whereas technical groups repaired the damage.

Lincoln devotes a whole bankruptcy to the Higgs boson and Higgs box, utilizing numerous prolonged analogies to assist clarify the significance of those thoughts to particle physics. within the ultimate bankruptcy, he describes what the invention of the Higgs boson tells us approximately our present figuring out of uncomplicated physics and the way the invention now retains scientists conscious over a nagging inconsistency of their favourite theory.

As available because it is interesting, the big Hadron Collider unearths the interior workings of this masterful success of know-how, in addition to the magnificent discoveries that may preserve it on the middle of the clinical frontier for the foreseeable future.

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Download E-books Transcendence: The Disinformation Encyclopedia of Transhumanism and the Singularity PDF

By Jay Cornell

Transhumanism is a world stream that advocates using technological know-how and know-how to beat the "natural" obstacles skilled by way of humanity via such advancements as:

  • the Singularity--the production of computer intelligences that exceed the capacities of our organic brains
  • the skill to copy person minds and placed them into solid-state our bodies or digital environments
  • individual keep an eye on over psychological and emotional states for reinforcing functionalities and/or ecstasies

Some of this is often taking place now. a few of it's nonetheless within the minds of dreamers.

In approximately 90 A-Z entries, Transcendence presents a multilayered examine the accelerating advances in man made intelligence, cognitive technology, genomics, info expertise, nanotechnology, neuroscience, house exploration, man made biology, robotics, and digital worlds which are making transhumanism a truth. Entries variety from Cloning and Cyborg Feminism to clothier infants and Memory-Editing medicines. furthermore, the publication notes ancient predecessors and personalities, either in mythology and history--ranging from Timothy Leary to Michael Jackson to Ray Kurzweil. It additionally introduces the tradition round Transhumanism, masking the entire geeky obsessions of the Transhumanist circulate.

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Download E-books Evolving Ourselves: How Unnatural Selection and Nonrandom Mutation are Changing Life on Earth PDF

“We are the first drivers of switch. we are going to without delay and ultimately confirm what lives, what dies, the place, and whilst. we're in a special section of evolution; the way forward for lifestyles is now in our hands.”

Why are premiums of stipulations like autism, bronchial asthma, weight problems, and asthma exploding at an exceptional velocity? Why are people residing longer, getting smarter, and having a long way fewer young ones? How may well your way of life have an effect on your unborn little ones and grandchildren? How will gene-editing applied sciences like CRISPR steer the process human evolution? If Darwin have been alive at the present time, how might he clarify this new international? might our progeny finally develop into a distinct species—or several?

In Evolving Ourselves, futurist Juan Enriquez and scientist Steve Gullans behavior a sweeping journey of ways people are altering the process evolution—sometimes deliberately, occasionally now not. For example:

   •  Globally, charges of weight problems in people approximately doubled among 1980 and 2014. What’s extra, there’s facts that different species, from pasture-fed horses to lab animals to deal with cats, also are getting fatter.
   •  As stated through U.S. govt organisations, the speed of autism rose by way of 131 percentage from 2001 to 2010, a rise that can not be attributed just to raises in analysis charges.
   •  300 years in the past, virtually not anyone with a significant nut hypersensitivity lived lengthy sufficient to breed. at the present time, regardless of an atmosphere during which foodstuff bronchial asthma have elevated by means of 50 percentage in exactly over a decade, 17 million american citizens that suffer from nutrition asthma continue to exist, thrive, and move their genes and behaviors directly to the following iteration.
   •  within the pre-Twinkie period, early people had relatively fit mouths. As we begun cooking, bathing, and utilizing antibiotics, the micro organism in bodies replaced dramatically and have become a ways much less assorted. this day the results are obvious not just in our enamel yet all through bodies and minds. 

Though those harbingers of switch are deeply unsettling, the authors argue that we're additionally in an epoch of great chance. New advances in biotechnology support us mitigate the harsh forces of traditional choice, from saving upfront born infants to gene treatments for sickle telephone anemia and different stipulations. As expertise like CRISPR enables us to take keep an eye on of our genes, we can regulate our personal species and lots of others—a great thing, on condition that our eventual survival would require house shuttle and colonization, enabled by means of a basic redecorate of our bodies.

Future people may well turn into nice caretakers of the planet, in addition to a extra different, extra resilient, gentler, and extra clever species—but provided that we make the fitting offerings now.

Intelligent, provocative, and positive, Evolving Ourselves is the last word advisor to the subsequent part of lifestyles on Earth.

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Download E-books Manual of Hypertension of the European Society of Hypertension, Second Edition PDF

Despite fresh advances in healthcare, high blood pressure is a number one reason behind loss of life and continues to be a disorder burden around the globe. Now in its moment version, the Manual of high blood pressure of the eu Society of Hypertension displays rising options that experience the aptitude to affect diagnostic and healing ways to this . Updating all fabric, this re-creation additionally delves right into a variety of parts that experience got heightened curiosity in recent times or became an issue of dialogue as a result of the debatable interpretation of the to be had data.

Topics include:

  • Background, heritage, and epidemiology of hypertension
  • Risk components reminiscent of pulse strain, excessive middle expense, weight problems, diabetes, and stress
  • Etiological and pathophysiological facets, together with hemodynamics and genetics
  • Hypertension-based harm to physique organs and systems
  • Blood strain measurements and different diagnostic procedures
  • Pharmacological, nonpharmacological, and clinical treatments
  • Hypertension in unique populations, together with diabetic sufferers, kids, while pregnant, and post-transplant
  • Cost-benefit facets of high blood pressure therapy and operating a high blood pressure center

Each subject is addressed in a layout that may be of curiosity not just to investigators and scholars who conduct studies on high blood pressure and its cardiovascular and renal problems, but in addition to clinicians desiring in-depth info on diagnostic and healing facets. The ebook is a necessary consultant to all aspects of this debilitating situation that continues to be a risk to public health.

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Download E-books Harmony and Conflict in the Living World PDF

By Alexander F. Skutch

From Publishers Weekly
Skutch (Life of the Flycatcher, etc.), an international well-known tropical ornithologist, has been publishing books and articles on birds and ordinary historical past for greater than 70 years. His most up-to-date paintings, in spite of the fact that, is an asymmetric discourse on his view of the wildlife. right here, Skutch argues that expanding concord is the dominant strength structuring all organic groups, together with human ones. eventually, he fails to craft a resounding argument partially simply because he by no means relatively offers a salient definition of concord and partly simply because he wanders to this point afield in his 9 chapters sharp concentration is rarely completed. frequently straying from his major aspect, Skutch makes a good number of debatable statements alongside the best way, contending, for instance, that team instead of person choice is quite common and that anthropomorphism is such a lot usually to not be shunned. He claims that "biodiversity has definitely develop into over the top, and is answerable for an incredible a part of the sufferings of animals, together with humans," and that "beneficence too frequently is helping incompetent people with heritable defects not just to outlive yet to beget childrens who're more likely to obtain the bad qualities in their mom and dad, thereby deteriorating the human stock." there's little facts to aid the accuracy of such statements--and loads of fresh paintings to them. Skutch turns out to disregard nearly all lately released fabric: purely of his seventy four references have been released in the final 10 years. 18 line drawings via Dana Gardner. (June)

From Library Journal
The elder statesman of tropical biology, Skutch used to be writing at the rainforests and biodiversity lengthy ahead of they turned buzzwords. Over 8 many years, he has produced approximately 30 books and 1000's of articles. A resident of Costa Rica because the Twenties, he has became more and more from looking at nature's procedures to philosophizing approximately them. right here he muses on nature's paradoxes and conflicts and but makes a case for a precept of concord as a becoming evolutionary strength. He dares to query why anthropomorphism could be a heresy in biology and successfully demanding situations our unquestioning mantra in compliment of range. Skutch specializes in crops, birds, and the foremost truths they could educate us. Woven into his philosophical cloth are recommendations on how what we see in nature will help us comprehend ourselves. reliable studying from an urbane, a professional guy whose paintings can be higher identified; for tutorial and bigger public libraries.DHenry T. Armistead, unfastened Lib. of Philadelphia

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